Organo-Metalloid Compounds
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Filtered Search Results
Medchemexpress LLC 1H-Isoindole-1,3(2H)-dione, 4-[[2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]ethyl]amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) | 2446474-09-3 | 96.6% | 50 MG
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Pomalidomide-PEG3-C2-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate. It incorporates the Pomalidomide based cereblon ligand and a 3-unit PEG linker, commonly used in PROTAC technology. This product is intended for research use only and has not been fully validated for medical applications.
- E3 ligase ligand-linker conjugate
- Incorporates Pomalidomide based cereblon ligand
- Utilizes a 3-unit PEG linker
- Used in PROTAC technology
- Targets Cereblon
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eMolecules 546-68-9 | Tetraisopropyl orthotitanate | Chem-Impex | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 1kg | 686070057
Tetraisopropyl orthotitanate | Chem-Impex | 546-68-9 | MFCD00008871 | 284.219 | C12H28O4Ti | 27.000 | [Ti+4].CC(C)[O-].CC(C)[O-].CC(C)[O-].CC(C)[O-] | 1kg | 686070057
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Medchemexpress LLC m-PEG3-Aminooxy | 248275-10-7 | 98.0% | C7H17NO4 | 25 MG
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m-PEG3-Aminooxy is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that contain two different ligands connected by a linker; one ligand targets an E3 ubiquitin ligase and the other targets a specific protein, enabling the degradation of target proteins through the intracellular ubiquitin-proteasome system.
- PEG-based linker
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- For research use only
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Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | >98.0% | 335.35 | C13H25N3O7 | 10 G
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Azido-PEG5-acid is an azide-terminated five-unit polyethylene glycol (PEG5) acid linker used for bioconjugation and linker synthesis. It functions as a click-chemistry reagent capable of undergoing azide-alkyne cycloaddition reactions and is commonly used in PROTAC and antibody-drug conjugate assembly.
- Azide functional group enables copper-catalyzed and strain-promoted click reactions.
- Five-unit PEG spacer provides solubility and flexibility for conjugation.
- High purity supports synthetic and bioconjugation applications.
- Available in multiple pack sizes for scalable workflows.
- Stable under recommended storage conditions to preserve reactivity.
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Medchemexpress LLC 4,7,10-trioxa-3-siladodecan-12-ol, 2,2,3,3-tetramethyl- | 201037-95-8 | MFCD30471718 | ≥98.0% | 264.43 | C12H28O4Si | 5 G
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TBDMS-PEG3-OH is a tert-butyldimethylsilyl (TBDMS)-protected triethylene glycol (PEG3) derivative used as a short PEG linker and building block in synthetic chemistry and drug-delivery research. It is a colorless to light yellow liquid (formula C12H28O4Si, MW 264.43) with high purity and defined storage conditions.
- Tert-butyldimethylsilyl-protected hydroxyl for selective deprotection.
- Short PEG3 spacer ideal for linker synthesis and conjugation.
- High purity: ≥98.0%.
- Available in bench-scale pack sizes, including 5 G.
- Stable when stored at recommended temperatures (pure: -20°C to 4°C).
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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 100 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. This click chemistry reagent contains an Azide group, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Click chemistry reagent
- Contains an Azide group
- Capable of copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with Alkyne groups
- Capable of strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN groups
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Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | 98.0% | 335.35 g/mol | C13H25N3O7 | 500 MG
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Azido-PEG5-acid is an azide-terminated, five-unit polyethylene glycol linker with a terminal carboxylic acid that enables click-chemistry bioconjugation reactions. It is used as a PROTAC and ADC linker and is compatible with copper-catalyzed azide-alkyne cycloaddition and strain-promoted cycloaddition reactions.
- Azide functional group for CuAAC and SPAAC reactions.
- Five-unit PEG spacer provides water solubility and flexibility.
- Terminal carboxylic acid enables amide or ester coupling.
- Typical purity ≥98.0%.
- Suitable for linker synthesis and bioconjugation applications.
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Medchemexpress LLC Ms-PEG5-t-butyl ester | 870487-48-2 | C16H32O9S | 50 MG
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Ms-PEG5-t-butyl ester is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs.
- PROTACs contain two different ligands connected by a linker.
- One ligand is for an E3 ubiquitin ligase, and the other is for the target protein.
- PROTACs exploit the intracellular ubiquitin-proteasome system.
- Used to selectively degrade target proteins.
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Medchemexpress LLC Azido-PEG3-DYKDDDDK TFA | 2243206-95-1 | 1242.20 | 25 MG
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Azido-PEG3-DYKDDDDK TFA is a multifunctional fusion tag used for the purification of recombinant proteins. It functions as a click chemistry reagent, featuring an azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC) with molecules containing alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Multifunctional fusion tag
- Purifies recombinant proteins
- Functions as a click chemistry reagent
- Contains an azide group
- Undergoes copper-catalyzed azide-alkyne cycloaddition reactions
- Participates in strain-promoted alkyne-azide cycloaddition reactions
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Medchemexpress LLC HO-PEG3-(CH2)6-Cl | 1355955-95-1 | 95.0% | 268.78 g·mol⁻¹ | C12H25ClO4 | 10 MG
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HO-PEG3-(CH2)6-Cl is a hydroxy-terminated PEG3 linker bearing a 6-chlorohexyl group, designed for assembling PROTACs and other bifunctional molecules. It serves as a spacer to connect targeting ligands and E3 ligase binders in targeted protein degradation research and is supplied for research use only.
- Hydroxy-terminated PEG3 spacer with a 6-chlorohexyl terminus.
- Designed for synthesis of PROTACs and bifunctional conjugates.
- Molecular formula C12H25ClO4; molecular weight 268.78 g·mol⁻¹.
- CAS number 1355955-95-1 for unambiguous identification.
- Reported purity about 95% from suppliers' product listings.
- Supplied in small milligram-scale packages for research synthesis.
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Medchemexpress LLC 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate | 62921-74-8 | MFCD06200731 | 98.8% | 318.39 g/mol | C14H22O6S | 500 MG
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m-PEG3-Tos is a tosyl-terminated polyethylene glycol (PEG) linker used as a reactive PEG3 spacer for conjugation and PROTAC synthesis. The tosyl leaving group enables nucleophilic substitution reactions to attach functional groups or linker arms in medicinal chemistry and bioconjugation workflows.
- Tosyl-terminated PEG3 linker for conjugation and PROTAC synthesis.
- Chemical name: 2-[2-(2-methoxyethoxy)ethoxy]ethyl 4-methylbenzene-1-sulfonate.
- CAS number: 62921-74-8.
- Molecular formula: C14H22O6S.
- Molecular weight: 318.39 g/mol.
- Purity: 98.8%.
- Package size: 500 MG.
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Medchemexpress LLC Methyl-PEG3-bromide 10g
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Methyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Ethanamine, 2-[2-[2-[(6-chlorohexyl)oxy]ethoxy]ethoxy]- | 1261350-60-0 | 95.0% | 267.79 | 25 MG
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NH2-PEG3-C6-Cl is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. This mechanism leverages the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Enables selective degradation of target proteins
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Medchemexpress LLC Azido-PEG3-C6-Cl | 1625717-44-3 | 95.30% | 293.79 | 25 MG
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Azido-PEG3-C6-Cl is a PEG-based PROTAC linker primarily used in the synthesis of PROTACs. It functions as a click chemistry reagent, capable of undergoing both copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne groups and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- PEG-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an azide group
- Participates in CuAAc reactions with alkyne groups
- Undergoes SPAAC reactions with DBCO or BCN groups
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Medchemexpress LLC M-PEG3-OMs | 74654-05-0 | >98% | C8H18O6S | 250 MG
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This product is m-PEG3-OMs, a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds that leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase with a ligand for the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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